Alonso-Curbelo D, Riveiro-Falkenbach E, Perez-Guijarro E, Cifdaloz M, Karras P, Osterloh L, Megias D, Canon E, Calvo TG, Olmeda D, Gomez-Lopez G, Grana O, Lobo V, Pisano DG, Wang HW, Ortiz-Romero P, Tormo D, Hoek KS, Peralto-Rodriguez JL, Joyce JA and Soengas MS (2014) RAB7 Controls Melanoma Progression by Exploiting a Lineage-Specific Wiring of the Endolysosomal Pathway Cancer Cell 26(1):61-76

Wawrzyniak JA, Bianchi-Smiraglia A, Bshara W, Mannava S, Ackroyd J, Bagati A, Omilian AR, Im M, Fedtsova N, Miecznikowski JC, Moparthy KC, Zucker SN, Zhu Q, Kozlova NI, Berman AE, Hoek KS, Gudkov AV, Shewach DS, Morrison CD and Nikiforov MA (2013) A purine nucleotide biosynthesis enzyme guanosine monophosphate reductase is a suppressor of melanoma invasion Cell Reports 5(2):493-507

Widmer DS, Hoek KS, Cheng PF, Eichhoff OM, Biedermann T, Raaijmakers MIG, Hemmi S, Dummer R and Levesque MP (2013) Hypoxia contributes to melanoma heterogeneity by triggering HIF1α-dependent phenotype switching J Invest Derm 133(10):2436-2443

Lobos-Gonzalez L, Aguilar L, Diaz J, Diaz N, Urra H, Torres V, Silva V, Fitzpatrick C, Lladser A, Hoek KS, Leyton L and Quest A (2013) E-cadherin determines Caveolin-1 tumor suppression or metastasis enhancing function in melanoma cells Pigment Cell Melanoma Res 26(4):555-570

Widmer DS, Cheng PF, Eichhoff OM, Belloni BC, Zipser MC, Schlegel NC, Javelaud D, Mauviel A, Dummer R and Hoek KS (2012) Systematic classification of melanoma cells by phenotype-specific gene expression mapping. Pigment Cell Melanoma Res 25(3):343-353

Javelaud D, Alexaki VI, Pierrat MJ, Hoek KS, Dennler S, Van Kempen L, Bertolotto C, Ballotti R, Saule S, Delmas V and Mauviel A (2011) GLI2 and M-MITF control exclusive gene expression programs and inversely regulate invasion in human melanoma cells. Pigment Cell Melanoma Res 24(5):932-943

Eichhoff OM, Weeraratna A, Zipser MC, Denat L, Widmer DS, Xu M, Kriegl L, Kirchner T, Larue L, Dummer R and Hoek KS (2011) Differential LEF1 and TCF4 expression is involved in melanoma cell phenotype switching. Pigment Cell Melanoma Res 24(4):631-642

Hoek KS (2011) MITF: the power and the glory. Pigment Cell Melanoma Res 24(2):262-263

Zipser MC, Eichhoff OM, Widmer DS, Schlegel NS, Schoenewolf NL, Stuart D, Liu W, Gardner H, Smith PD, Nuciforo P, Dummer R and Hoek KS (2011) A proliferative melanoma cell phenotype is responsive to RAF/MEK inhibition independent of BRAF mutation status. Pigment Cell Melanoma Res 24(2):326-333

Hoek KS (2011) Pathogenesis of malignant melanoma. Skin Cancer - A World-Wide Perspective (2):55-64

Hoek KS and Goding CR (2010) Cancer stem cells versus phenotype-switching in melanoma. Pigment Cell Melanoma Res 23(6):746-759

Manga P, Hoek KS, Davids LM and Leachman SA (2010) From melanocyte to malignant metastatic melanoma Dermatol Res Prac Article ID 798324

Hoek KS (2010) The new melanoma. Dermatol Helv 22(10):28-30

Alexaki VI, Javelaud D, van Kempen L, Mohammad K, Dennler S, Luciani F, Hoek KS, Juarez P, Goydos J, Fournier P, Sibon C, Bertolotto C, Verrecchia F, Saule S, Delmas V, Ballotti R, Larue L, Saiag P, Guise T and Mauviel A (2010) GLI2-Mediated Melanoma Invasion and Metastasis J Natl Cancer Inst 102(15):1148-1159

Hoek KS (2010) Exploring melanoma's massively parallel universe Pigment Cell Melanoma Res 23(3):306-307

Eichhoff OM, Zipser MC, Xu M, Weeraratna AT, Mihic D, Dummer R and Hoek KS (2010) The immunohistochemistry of invasive and proliferative phenotype switching in melanoma: a case report. Melanoma Res 20(4):349-355

Orgaz JL, Ladhani O, Hoek KS, Fernandez-Barral A, Mihic D, Aguilera O, Seftor EA, Bernad A, Rodriguez-Peralto JL, Hendrix MJC, Volpert OV and Jimenez B (2009) Loss of pigment epithelium-derived factor enables migration, invasion and metastatic spread of human melanoma. Oncogene 28(47):4147-4161

OConnell MP, Fiori JL, Kershner EK, Frank BP, Indig FE, Taub DD, Hoek KS and Weeraratna AT (2009) Heparan sulfate proteoglycan modulation of WNT5A signal transduction in metastatic melanoma cells J Biol Chem 284(42):28704-28712

Grigoriadis A, Caballero OL, Hoek KS, da Silva L, Chen YT, Shin SJ, Jungbluth AA, Miller LD, Clouston D, Cebon J, Old LJ, Lakhani SR, Simpson AJG and Munro Neville A (2009) CT-X antigen expression in human breast cancer P Natl Acad Sci USA 106(32):13493-13498

Schlegel NC, Eichhoff OM, Hemmi S, Mihic D, Werner S, Dummer R and Hoek KS (2009) Id2 suppression of p15 counters TGF-β-mediated growth inhibition of melanoma cells. Pigment Cell Melanoma Res 22(4):445-453

OConnell MP, Fiori JL, Baugher KM, Indig FE, French AD, Camilli TC, Frank BP, Earley R, Hoek KS, Hasskamp JH, Elias EG, Taub DD, Bernier M and Weeraratna AT (2009) Wnt5A activates the calpain-mediated cleavage of Filamin A J Invest Dermatology 129(7):1782-1789

Fiori JL, Zhu TN, OConnell MP, Hoek KS, Indig FE, Frank BP, Morris C, Kole S, Hasskamp J, Elias G, Weeraratna AT and Bernier M (2009) Filamin A modulates kinase activation and intracellular trafficking of epidermal growth factor receptors in human melanoma cells. Endocrinology 150(6):2551-2560

Hoek KS (2009) Gene expression profiling: GAD help us all. The Society for Melanoma Research Newsletter 1(8):3-4

Almanzar G, Olkhanud PB, Bodogai M, Dellagnola C, Baatar D, Hewitt SM, Ghimenton C, Tummala MK, Weeraratna AT, Hoek KS, Kouprina N, Larionov V and Biragyn A (2009) Sperm-derived SPANX-B is a clinically relevant tumor antigen that is expressed in human tumors and readily recognized by human CD4+ and CD8+ cells. Clinical Cancer Res 15(6):1954-1963

Winklmeier A, Poser I, Hoek KS and Bosserhoff A (2009) Loss of full length CtBP1 expression enhances the invasive potential of human melanoma. BMC Cancer 9(1):52

Hoek KS, Eichhoff OM, Widmer DS and Dummer R (2009) Stemming the flood. Pigment Cell Melanoma Res 22(1):6-7

Hoek KS (2009) Melanoma progression, gene expression and DNA microarrays. G Ital Dermatol Venereol 144(1):39-49

Mnich CD, Hoek KS, Virkki LV, Farkas A, Dudli C, Laine E, Urosevic M and Dummer R (2009) Green tea extract reduces induction of p53 and apoptosis in UVB-irradiated human skin independent of transcriptional controls. Exp Dermatol 18(1):69-77

Dissanayake SK, Olkhanud PB, OConnell MP, Carter A, French AD, Camilli TC, Emeche CD, Hewitt KJ, Rosenthal DT, Leotlela PD, Wade MS, Yang SW, Brant L, Nickoloff BJ, Messina JL, Biragyn A, Hoek KS, Taub DD, Longo DL, Sondak VK, Hewitt SM and Weeraratna AT (2008) Wnt5A Regulates Expression of Tumor-Associated Antigens in Melanoma via Changes in Signal Transducers and Activators of Transcription 3 Phosphorylation. Cancer Res 68(24):10205-10214

Hoek KS, Schlegel NC, Eichhoff OM, Widmer DS, Praetorius C, Einarsson SO, Valgeirsdottir S, Bergsteinsdottir K, Schepsky A, Dummer R and Steingrimsson E (2008) Novel MITF targets identified using a two-step DNA microarray strategy. Pigment Cell Melanoma Res 21(6):665-676

Hoek KS (2008) GeneSifter, leading the blind Pigment Cell Melanoma Res 21(5):588-589

Hoek KS, Eichhoff OM, Schlegel NC, Döbbeling U, Kobert N, Schaerer L, Hemmi S and Dummer R (2008) In vivo switching of human melanoma cells between proliferative and invasive states. Cancer Res 68(3):650-656

Beyeler M, Hoek KS and Dummer R (2008) Voodoo medicine still going strong: a tale of melanoma, faith, and failure. Arch Dermatol 144(1):121-122

Hoek KS (2007) DNA microarray analyses of melanoma gene expression: a decade in the mines. Pigment Cell Res 20(6):466-484

Denk AE, Bettstetter M, Wild PJ, Hoek KS, Bataille F, Dietmaier W and Bosserhoff AK (2007) Loss of maspin expression contributes to a more invasive potential in malignant melanoma. Pigment Cell Res 20(2):112-119

Mnich CD, Hoek KS, Oberholzer PA, Seifert B, Hafner J, Dummer R and Mihic D (2007) Reduced pSmad2 immunodetection correlates with increased primary melanoma thickness. Melanoma Res 17(2):131-136

Carreira S, Goodall J, Denat L, Rodriguez M, Nuciforo P, Hoek KS, Testori A, Larue L and Goding CR (2006) Mitf regulation of Dia1 controls melanoma proliferation and invasiveness. Genes Dev 20(24):3426-3439

Hoek KS, Schlegel NC, Brafford P, Sucker A, Ugurel S, Kumar R, Weber BL, Nathanson KL, Phillips DJ, Herlyn M, Schadendorf D and Dummer R (2006) Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature. Pigment Cell Res 19(4):290-302

Smith AP, Hoek KS and Becker D (2005) Whole-genome expression profiling of the melanoma progression pathway reveals marked molecular differences between nevi/melanoma in situ and advanced-stage melanomas. Cancer Biol Ther 4(9):1018-1029

Hoek KS, Rimm DL, Williams KR, Zhao H, Ariyan S, Lin A, Kluger HM, Berger AJ, Cheng E, Trombetta ES, Wu T, Niinobe M, Yoshikawa K, Hannigan GE and Halaban R (2004) Expression profiling reveals novel pathways in the transformation of melanocytes to melanomas. Cancer Res 64(15):5270-5282

Dummer R, Urosevic M, Kempf W, Hoek KS, Hafner J and Burg G (2003) Imiquimod in basal cell carcinoma: how does it work? Br J Dermatol 149(S66):57-58

Dummer R, Urosevic M, Hoek KS, Haffner A and Burg G (2003) Exploring primary cutaneous B-cell lymphoma by microarray technology. J Invest Dermatology 120(5):vii-viii

Ma AS, Moran-Jones K, Shan J, Munro TP, Snee MJ, Hoek KS and Smith R (2002) Heterogeneous nuclear ribonucleoprotein A3, a novel RNA trafficking response element-binding protein. J Biol Chem 277(20):18010-18020

Shan J, Moran-Jones K, Munro TP, Kidd GJ, Winzor DJ, Hoek KS and Smith R (2000) Binding of an RNA trafficking response element to heterogeneous nuclear ribonucleoproteins A1 and A2. J Biol Chem 275(49):38286-38295

Hoek KS, Kidd GJ, Carson JH and Smith R (1998) hnRNP A2 selectively binds the cytoplasmic transport sequence of myelin basic protein mRNA. Biochemistry 37(19):7021-7029

Hoek KS, Milne JM, Grieve PA, Dionysius DA and Smith R (1997) Antibacterial activity in bovine lactoferrin-derived peptides. Antimicrob Agents Chemother 41(1):54-59

Dionysius DA, Hoek KS, Milne JM and Slattery SL (1993) Trypsin-like enzyme from sand crab (Portunus pelagicus): purification and characterization. J Food Sci 58(4):780-784